Determination of rilpivirine (TMC-278) plasma concentrations by the conventional LC-MS method
نویسندگان
چکیده
منابع مشابه
Development and application of a simple LC-MS method for the determination of plasma rilpivirine (TMC-278) concentrations.
Rilpivirine (TMC-278) is a second-generation non-nucleoside reverse transcriptase inhibitor that is high potent against both wild-type and drug-resistant HIV-1 strains. Therefore, rilpivirine is expected to treat therapy-experienced patients who failed to use current drugs due to the emergence of drug-resistant HIV mutants. The quantification of rilpivirine in human plasma is important to suppo...
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ژورنال
عنوان ژورنال: Journal of the International AIDS Society
سال: 2012
ISSN: 1758-2652
DOI: 10.7448/ias.15.6.18361